This study provides current data on key questions about retraction of scientific articles. Findings confirm that the rate of retractions remains low but is increasing. The most commonly cited reason for retraction was research error or inability to reproduce results; the rate from research misconduct is an underestimate, since some retractions necessitated by research misconduct were reported as being due to inability to reproduce. Retraction by parties other than authors is increasing, especially for research misconduct. Although retractions are on average (...) occurring sooner after publication than in the past, citation analysis shows that they are not being recognised by subsequent users of the work. Findings suggest that editors and institutional officials are taking more responsibility for correcting the scientific record but that reasons published in the retraction notice are not always reliable. More aggressive means of notification to the scientific community appear to be necessary. (shrink)

Some factors affecting marital distances have been studied in two Outer Hebridean islands, Harris (843 marriages) and Barra (444 marriages), over the period 1855-1990. In each island marital distances fell before 1900, but then rose to their greatest values after the 1950s. Fishermen generally married at the shortest distances and men in land-based occupations at the longest. The depression in the fishing industry during the 1880s and early 1890s was associated with reductions in marital distances, especially among fishermen. In the (...) different regions of Harris, marital distances were least in the south-east, where settlement was most dense, and greatest in the south-west where it was most sparse. (shrink)

Studies have shown that as MRI T2 relaxation time lengthens there is a shift toward more unbound or “free-water” and less partitioning of the protein/lipid molecules per unit volume. A shift toward less water partitioning or lengthened MRI T2 relaxation time is linearly related to reduced high frequency EEG amplitude, reduced short distance EEG coherence, increased long distance EEG coherence, and reduced cognitive functioning (Thatcher et al. 1998a; 1998b).

Herein we examine the theory and practical limits of designing a voluntary incentive scheme to protect endangered species on private land. We consider both an ay-ante scheme, in which a contract to the landholder depends only on what the landholder reports, and an ay-post scheme, in which a contract to the landholder depends on reports from all landowners. Except in special cases, the ex-ante scheme never implements the full information allocation, and can actually set aside too much land. In contrast, (...) expected habitat size under the ex-post scheme is smaller than both the ex-ante and full information allocations. (C) 2001 Elsevier Science (USA). (shrink)

Objective: To assess the adequacy of the process of informed consent for surgical patients at the University Hospital of the West Indies. Method: The study is a prospective, cross-sectional, descriptive study. 210 patients at the University Hospital of the West Indies were interviewed using a standardised investigator-administered questionnaire, developed by the authors, after obtaining witnessed, informed consent for participation in the study. Data were analysed using SPSS V.12 for Windows. Results: Of the patients, 39.4% were male. Of the surgical procedures, (...) 68.6% were scheduled, 7.6% urgent and 23.8% emergency, 35.2% were minor and 64.8% major. Information imparted/received was acceptable in 40% of cases, good in 24% and inadequate (unacceptable) in 36% of cases. Almost all (97.6%) patients stated that they understood why an operation was planned and 93.3% thought that they had given informed consent. Most (95.2%) thought that they had free choice and made up their own mind. A quarter (25.2%) of all patients were told that it was mandatory for them to sign the form. There was a discussion of possible side effects and complications in 56.7% of patients. Conclusions: This study clearly indicates that surgical patients at the University Hospital of the West Indies feel that they have given informed consent. However, it also suggests that more information should be given to patients for consent to be truly informed. (shrink)

The European Clinical Trials Directive (EU 2001; 2001/20/EC) was introduced to improve the efficiency of commercial and academic clinical trials. Concerns have been raised by interested organizations and institutions regarding the potential for negative impact of the Directive on non-commercial European clinical research. Interested researchers within the European Group for Blood and Marrow Transplantation (EBMT) were surveyed to determine whether researcher experiences confirmed this view. Following a pilot study, an internet-based questionnaire was distributed to individuals in key research positions in (...) the European haemopoietic SCT community. Seventy-one usable questionnaires were returned from participants in different EU member states. The results indicate that the perceived impact of the European Clinical Trials Directive has been negative, at least in the research areas of interest to the EBMT. (shrink)

This collection of essays, addresses, and one interview come from the years 1966-73 and cover a wide spectrum of interest, dealing with such general topics as 'The Absence of God in Modern Culture' and 'The Future of Christianity.'.

The posterior parietal cortex (PPC) is the most likely site where egocentric spatial relationships are represented in the brain. PPC cells receive visual, auditory, somaesthetic, and vestibular sensory inputs; oculomotor, head, limb, and body motor signals; and strong motivational projections from the limbic system. Their discharge increases not only when an animal moves towards a sensory target, but also when it directs its attention to it. PPC lesions have the opposite effect: sensory inattention and neglect. The PPC does not seem (...) to contain a “map” of the location of objects in space but a distributed neural network for transforming one set of sensory vectors into other sensory reference frames or into various motor coordinate systems. Which set of transformation rules is used probably depends on attention, which selectively enhances the synapses needed for making a particular sensory comparison or aiming a particular movement. (shrink)

In the opening chapter of the Iudicium de Dinarcho Dionysius quotes a passage from the Περì μωνμων of Demetrius Magnes, mat the end of which come the words δ λξις ςτ το Δεινρχου κυρως θικ πθος κινοσα σχεδòν τ πικρí μóνον καì τ τóν το Δημοσθθενικο χαρακτρος λειπομνη το δ πιθανο καì κυρíιυ μηδν νδονσα. [I have deliberately omitted all punctuation marks, because the punctuation of this sentence is still doubtful, though I hope to suggest a possible interpretation of its (...) meaning at the end of this article.] Now there is nothing in this sentence or in the words preceding it to indicate beyond all possibility of doubt the precise meaning ofκυρíως θικ. And in such circumstances, to allow free play to personal prejudices regarding the significance of thephrase is more than dangerous. The whole problem of θικ λξις has been treated too cursorily. If one mentions the phrase to a non-professional student of Greek, who, however, has some acquaintance with the Attic orators, he immediately replies: ‘I suppose you mean the sort of thing you meet in Lysias.’ And he is to beexcused, because, after all, that is the predominant meaning of the term. But it has other senses, and therefore one must fight shy of vague statements like that of Finke, who, after quoting the above lines, comment: ‘Demetrius Magnus attribuit ei τν κυρíαν λξιν qua non sit Demosthene inferior’; or of Burgess, who enumerates qualities, ideas, and topics ‘of special value to the epideictic and court orators, ’ among which appears θοποια which he merely translates ‘impersonation or delineation of character, ’ without offering any further comment. Sandys talks of ‘the ethical warmth of colouring, by which the dullest details are lit up with a fresh life and interest.’ Gromska is even more vague (and seems almost to confuse θς and χαρακτρ: ‘Grammatici antiqui, qui de Hyperide tractabant, de eloquentiae eius genere disputabant, orationum Hyperidearum compositionem et θς respicientes, i.e. quantum in arte rhetorica et oratoria valeret, examinantes.’ In the hope, therefore, of being able to represent the difficulty inherent in these lines, and of attempting to remove it, or at any rate to shed a broader beam of light upon it than has been shed hitherto, I propose to review very briefly the fluctuations of meaning in the life of this phrase and its equivalents, as we find them used in the critical writings of the Greek philosophers and rhetoricians. (shrink)

Neglect of the ‘codices deteriores’ has caused the ascription of a considerable number of readings in Cic. De Diuin. to the conjectures of scholars of the fifteenth, sixteenth, and later centuries, though manuscript evidence, in some cases of a much earlier date, is to be found. Even if the presence of such readings in the manuscripts is due to conjecture and to no other cause, credit for priority should be given to the manuscripts. The following notes are restricted to the (...) evidence of the London MSS. (shrink)

For a computable structure A\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathcal{A}}$$\end{document}, there may not be a computable infinitary Scott sentence. When there is a computable infinitary Scott sentence φ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\varphi}$$\end{document}, then the complexity of the index set I\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${I}$$\end{document} is bounded by that of φ\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\varphi}$$\end{document}. There are results giving “optimal” Scott sentences for (...) structures of various familiar kinds. These results have been driven by the thesis that the complexity of the index set should match that of an optimal Scott sentence. In this note, it is shown that the thesis does not always hold. For a certain subgroup of Q\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\mathbb{Q}}$$\end{document}, there is no computable d-Σ2\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\Sigma_2}$$\end{document} Scott sentence, even though the index set is d-Σ20\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${\Sigma^0_2}$$\end{document}. (shrink)

The most important events of the immediately preceding period--1945-1954--were attempts at general readings of Descartes' thought by Jean Laporte, Fernand Alquié, and Martial Guéroult. In Le Rationalisme de Descartes Laporte struck sharply at stereotype by insisting that Descartes was not a rationalist. Deftly exploiting such issues as the soul-body union, the knowledge of the infinite and the faith-reason relationship, he draws the conclusion that "... if it were necessary to characterize Descartes' philosophy by one name, the name which would fit (...) it best, all paradox aside, would be empiricism, radical and integral empiricism." The readings of both Alquié and Gueroult are carefully attuned to the development in Descartes' thought. In La Découverte Métaphysique de l'Homme chez Descartes, the former maintains that this development is dominated by the progressive discovery of the meaning of man. Guéroult takes a remark from the Discourse on Method as key to the unfolding of Descartes' thought. The "long chains of reasons, so simple and easy, which geome- tricians use to arrive at their most difficult demonstrations..." are the central inspiration of Descartes selon l'Ordre des Raisons. Cartesianism, it is maintained, developed primarily by deductive movement along these chains. (shrink)

In recent years, a series of key social, political and economic events has placed the critique of capitalism very much on the theoretical agenda. Responding to these developments, many have begun to express the need for a rapprochement between social criticism and the critique of political economy. The present essay represents a contribution to the recovery of the project that was once synonymous with critical theory itself via a critical engagement with the early writings of Jürgen Habermas. Not only is (...) Habermas’ explicit engagement with the critique of political economy among the most substantial to be found within the mainstream tradition of critical theory, his early social-theoretical insights into the emergent ‘primacy of the political’ in late capitalism can be taken as representative of a number of broader trends in late-20th-century thought which sought to go beyond the premises and categories of Marx’s economic works. Simply put, no reappraisal of the relationship between critical theory and the critique of political economy can succeed, I submit, without taking seriously Habermas’s path-breaking and wide-ranging innovations. (shrink)

In Corp. Gloss. Lat. V. 435–490 Goetz published excerpts from the A A glossary. Further interesting items were published by C. Theander in Eranos XXIII 51–61, 167–176. The complete glossary is now being prepared for the press, and Professor W. M. Lindsay has kindly communicated to me some of the new items which may possibly contain quotations from classical authors. The most interesting of them is the following: MA 2 ‘Mabortia res quae ad pugnam pertinet unde moenia funduntur vel res (...) Martia.’. (shrink)

In this paper the authors argue that ethical considerations are relevant for evaluating animal production systems and that in consequence agrologists should seriously consider the arguments of animal welfare supporters. Furthermore, the authors point out the ethical basis for some (though not all) of the conclusions proposed by supporters of animal welfare. In consequence it is necessary to determine the nature of animal welfare and methods of evaluating the welfare of animals and to recognize when production systems fail to satisfy (...) the needs of animals. (shrink)

The study of low penetrance gene variants in a complex genetic disorder such as stroke does not pose the same risks and benefits as a study of highly penetrant mutations.1 Because of the nature of their disease, however, stroke patients may not understand the information given when they are asked for consent to participate in research and are potentially vulnerable subjects. In a systematic review of publications on ischaemic stroke genetics, we assessed the way in which informed consent and ethics (...) committee approval are reported.MethodsWe searched the MEDLINE database for stroke genetics studies published in English between January 2000 and January 2002, using the medical subject heading term “cerebrovascular disorders, genetics of” plus the text words “ischaemic” and “stroke.”2 We included only original clinical trials and observational studies of human genetic risk factors for ischaemic stroke.Both authors independently reviewed every article. We used standardised forms to record whether an explicit statement described informed consent and institutional review board procedures. We also recorded whether …. (shrink)

The following texts and comments are a supplement to ‘Democritus on Politics and the Care of the Soul’, CQ 39 , 307–31 . The Democritean fragments there were quoted only in translation; detailed commentary on them would have taken up too much space and clogged the argument. They make their appearance here in the same order as they did there, preceded by a thumb-nail résumé of that argument and of their place in it. Text, spelling and numbering is that of (...) the standard edition: H. Diels, W. Kranz, Die Fragmente der Vorsokratiker . Reference will also be made to collections by P. Natorp, Die Ethika des Demokritos , S. Y. Luria, Democritea and G. Ibscher, Demócrito y sus sentencias sobre ética y education , as well as to translations by V. E. Alfieri, Gli Atomisti , K. Freeman, Ancilla to the Presocratics and J. Barnes, Early Greek Philosophy. (shrink)

Bertrand de Jouvenel was a renowned French philosopher and political economist. In Sovereignty he turned his attention to the relationship between the distribution of power and the creation of an ethical society. More specifically, he was concerned with the potential confusion of the body politic resulting from the development of increasingly dynamic and nebulous social conditions. The text is written in an exploratory fashion, reflecting the authorial perception of an ambiguity in modern political structures. This translated Cambridge edition, which was (...) first published in 1957, was derived from a 1955 French original. It constitutes an important contribution to post-war political theory that will remain of value to anyone with an interest in questions relating to political structures and the nature of authority. (shrink)